![]() ![]() They may recommend changing your dosage, particularly during times of stress. If you develop uncomfortable side effects, contact your prescribing doctor. Doing so can mean that your body will absorb them more quickly. Taking pills whole: You should not crush pills.Be sure to discuss the FDA recall of certain brands of extended-release metformin to ensure that you get a safe version. This type of metformin releases slowly over time and typically has milder side effects. Taking extended-release metformin: You can talk with a doctor to find out whether extended-release metformin might be right for you.Taking metformin with a meal: Taking metformin with a meal can help reduce your chances of developing an upset stomach or digestive discomfort.A typical starting dose is 500 milligrams. Starting with a low dose: It’s best to start at a low dose and work up over time to reduce your chances of developing side effects.You can minimize your chances of developing side effects by: Most of the common side effects of metformin involve your digestive system. Make sure to talk with the doctor who prescribed metformin before you stop taking it. Your vitamin B12 levels may improve if you stop taking metformin or take vitamin B12 supplements. If you think you may have anemia, make an appointment with your doctor to have your red blood cell levels checked. The more common symptoms of anemia include: If you don’t get much vitamin B12 or calcium through your diet, you may be at higher risk of having very low vitamin B12 levels. In rare cases, this can cause anemia (low levels of red blood cells). Metformin can decrease the levels of vitamin B12 in your body. See the risk factors section for more information about factors that raise your risk of this complication. Taking some other medications, including corticosteroids and blood pressure medications, with metformin may increase your risk of lactic acidosis. Metformin-associated lactic acidosis has an estimated death rate of up to 50%. ![]() If you have trouble breathing, call 911 or your local emergency number or go to the nearest emergency room. ![]()
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